PDB Information

PDB4BCQ
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity.
Hole, A.J., Baumli, S., Shao, H., Shi, S., Pepper, C., Fischer, P.M., Wang, S., Endicott, J.A., Noble, M.E.M.
J.Med.Chem.
HeaderTransferase/Cell Cycle
Released2012-10-02
Resolution2.400
CATH Insert Date20 Jan, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 21 Jan, 2013 Chopped
B 21 Jan, 2013 Chopped
C 21 Jan, 2013 Chopped
D 21 Jan, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4bcqA01 11 Feb, 2013 3.30.200.20 Assigned
4bcqA02 11 Feb, 2013 1.10.510.10 Assigned
4bcqB01 24 Jan, 2013 1.10.472.10 Assigned
4bcqB02 24 Jan, 2013 1.10.472.10 Assigned
4bcqC01 11 Feb, 2013 3.30.200.20 Assigned
4bcqC02 11 Feb, 2013 1.10.510.10 Assigned
4bcqD01 24 Jan, 2013 1.10.472.10 Assigned
4bcqD02 24 Jan, 2013 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P30274 CCNA2_BOVIN Bos taurus Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P30274 CCNA2_BOVIN Bos taurus Cyclin-A2