PDB Information

PDB4BCP
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Substituted 4-(Thiazol-5-Yl)-2-(Phenylamino)Pyrimidines are Highly Active Cdk9 Inhibitors: Synthesis, X-Ray Crystal Structure, Sar and Anti-Cancer Activities.
Shao, H., Shi, S., Huang, S., Hole, A., Abbas, A.Y., Baumli, S., Liu, X., Lam, F., Foley, D.W., Fischer, P.M., Noble, M., Endicott, J.A., Pepper, C., Wang, S.
J.Med.Chem.
HeaderTransferase/Cell Cycle
Released2012-10-02
Resolution2.260
CATH Insert Date07 Jul, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped
C 08 Jul, 2013 Chopped
D 08 Jul, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4bcpA01 09 Aug, 2013 3.30.200.20 Assigned
4bcpA02 09 Aug, 2013 1.10.510.10 Assigned
4bcpB01 09 Aug, 2013 1.10.472.10 Assigned
4bcpB02 09 Aug, 2013 1.10.472.10 Assigned
4bcpC01 09 Aug, 2013 3.30.200.20 Assigned
4bcpC02 09 Aug, 2013 1.10.510.10 Assigned
4bcpD01 09 Aug, 2013 1.10.472.10 Assigned
4bcpD02 09 Aug, 2013 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2