PDB 4bco

PDB Information

PDB4BCO
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity.
Hole, A.J., Baumli, S., Shao, H., Shi, S., Pepper, C., Fischer, P.M., Wang, S., Endicott, J.A., Noble, M.E.M.
J.Med.Chem.
HeaderTransferase/Cell Cycle
Released2012-10-02
Resolution2.050
CATH Insert Date20 Jan, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 21 Jan, 2013 Chopped
B 21 Jan, 2013 Chopped
C 21 Jan, 2013 Chopped
D 21 Jan, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4bcoA01 11 Feb, 2013 3.30.200.20 Assigned
4bcoA02 11 Feb, 2013 1.10.510.10 Assigned
4bcoB01 24 Jan, 2013 1.10.472.10 Assigned
4bcoB02 24 Jan, 2013 1.10.472.10 Assigned
4bcoC01 11 Feb, 2013 3.30.200.20 Assigned
4bcoC02 11 Feb, 2013 1.10.510.10 Assigned
4bcoD01 24 Jan, 2013 1.10.472.10 Assigned
4bcoD02 24 Jan, 2013 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P30274 CCNA2_BOVIN Bos taurus Cyclin-A2
P30274 CCNA2_BOVIN Bos taurus Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2