PDB 4bbx

PDB Information

PDB4BBX
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Potent, Selective and Orally Active Pde10A Inhibitor for the Potential Treatment of Schizophrenia.
Bartolome-Nebreda, J.M., Delgado, F., Martin, M.L., Martinez-Viturro, C.M., Pastor, J., Tong, H.M., Iturrino, L., Macdonald, G.J., Sanderson, W.E., Megens, A., Langlois, X., Somers, M., Vanhoof, G., Conde Ceide, S.
J.Med.Chem.
HeaderHydrolase
Released2012-09-28
Resolution2.500
CATH Insert Date20 Oct, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 21 Oct, 2013 Chopped
B 21 Oct, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4bbxA00 30 Oct, 2013 1.10.1300.10 Assigned
4bbxB00 30 Oct, 2013 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A