PDB 4bb5

PDB Links
Overview

PDB Information

PDB	4BB5
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Free-Wilson and Structural Approaches to Co-Optimising Human and Rodent Isoform Potency for 11Beta-Hydroxysteroid Dehydrogenase Type 1 (11Beta-Hsd1) Inhibitors Goldberg, F.W., Leach, A.G., Scott, J.S., Snelson, W.L., Groombridge, S.D., Donald, C.S., Bennett, S.N.L., Bodin, C., Morentin Gutierrez, P., Gyte, A.C. J.Med.Chem.
Header	Oxidoreductase
Released	2012-09-20
Resolution	2.200
CATH Insert Date	02 Dec, 2012

PDB Images (9)

Image of CATH 4bb5

4bb5

PDB 4bb5

Image of CATH 4bb5A

4bb5A

PDB Chain 4bb5A

Image of CATH 4bb5B

4bb5B

PDB Chain 4bb5B

Image of CATH 4bb5C

4bb5C

PDB Chain 4bb5C

Image of CATH 4bb5D

4bb5D

PDB Chain 4bb5D

Image of CATH 4bb5A00

4bb5A00

CATH Domain 4bb5A00

Image of CATH 4bb5B00

4bb5B00

CATH Domain 4bb5B00

Image of CATH 4bb5C00

4bb5C00

CATH Domain 4bb5C00

Image of CATH 4bb5D00

4bb5D00

CATH Domain 4bb5D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	31 Dec, 2012	Chopped
B	31 Dec, 2012	Chopped
C	31 Dec, 2012	Chopped
D	31 Dec, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4bb5A00	02 Jan, 2013	3.40.50.720	Assigned
4bb5B00	03 Jan, 2013	3.40.50.720	Assigned
4bb5C00	03 Jan, 2013	3.40.50.720	Assigned
4bb5D00	03 Jan, 2013	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1