PDB Information

PDB4B77
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Core Refinement Toward Permeable Beta-Secretase (Bace-1) Inhibitors with Low Herg Activity.
Ginman, T., Viklund, J., Malmstrom, J., Blid, J., Emond, R., Forsblom, R., Johansson, A., Kers, A., Lake, F., Sehgelmeble, F., Sterky, K.J., Bergh, M., Lindgren, A., Johansson, P., Jeppsson, F., Falting, J., Gravenfors, Y., Rahm, F.
J.Med.Chem.
HeaderHydrolase
Released2012-08-16
Resolution1.800
CATH Insert Date04 Aug, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4b77A01 14 Aug, 2013 2.40.70.10 Assigned
4b77A02 14 Aug, 2013 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1