PDB 4axm
PDB Information
| PDB | 4AXM |
| Method | X-RAY DIFFRACTION |
| Host Organism | ESCHERICHIA COLI |
| Gene Source | HOMO SAPIENS |
| Primary Citation | Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-Ray Crystal Structure Analysis with Human Cathepsin L
Chemmedchem
|
| Header | Hydrolase |
| Released | 2012-06-13 |
| Resolution | 2.800 |
| CATH Insert Date | 07 Jul, 2013 |
PDB Images (13)
4axm
PDB 4axm
4axmA
PDB Chain 4axmA
4axmB
PDB Chain 4axmB
4axmF
PDB Chain 4axmF
4axmI
PDB Chain 4axmI
4axmL
PDB Chain 4axmL
4axmO
PDB Chain 4axmO
4axmA00
CATH Domain 4axmA00
4axmB00
CATH Domain 4axmB00
4axmF00
CATH Domain 4axmF00
4axmI00
CATH Domain 4axmI00
4axmL00
CATH Domain 4axmL00
4axmO00
CATH Domain 4axmO00
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 08 Jul, 2013 | Chopped |
| B | 08 Jul, 2013 | Chopped |
| F | 08 Jul, 2013 | Chopped |
| I | 08 Jul, 2013 | Chopped |
| L | 08 Jul, 2013 | Chopped |
| O | 08 Jul, 2013 | Chopped |
CATH Domains (6)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4axmA00 | 09 Aug, 2013 | 3.90.70.10 | Assigned |
| 4axmB00 | 09 Aug, 2013 | 3.90.70.10 | Assigned |
| 4axmF00 | 09 Aug, 2013 | 3.90.70.10 | Assigned |
| 4axmI00 | 09 Aug, 2013 | 3.90.70.10 | Assigned |
| 4axmL00 | 09 Aug, 2013 | 3.90.70.10 | Assigned |
| 4axmO00 | 09 Aug, 2013 | 3.90.70.10 | Assigned |
UniProtKB Entries (6)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P07711 | CATL1_HUMAN | Homo sapiens | Cathepsin L1 |
| P07711 | CATL1_HUMAN | Homo sapiens | Cathepsin L1 |
| P07711 | CATL1_HUMAN | Homo sapiens | Cathepsin L1 |
| P07711 | CATL1_HUMAN | Homo sapiens | Cathepsin L1 |
| P07711 | CATL1_HUMAN | Homo sapiens | Cathepsin L1 |
| P07711 | CATL1_HUMAN | Homo sapiens | Cathepsin L1 |
