PDB 4aq3

PDB Information

PDB4AQ3
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Identification of a Phenylacylsulfonamide Series of Dual Bcl-2/Bcl-Xl Antagonists.
Perez, H.L., Banfi, P., Bertrand, J.A., Cai, Z.W., Grebinski, J.W., Kim, K., Lippy, J., Modugno, M., Naglich, J., Schmidt, R.J., Tebben, A., Vianello, P., Wei, D.D., Zhang, L., Galvani, A., Lombardo, L.J., Borzilleri, R.M.
Bioorg.Med.Chem.Lett.
HeaderApoptosis
Released2012-04-12
Resolution2.400
CATH Insert Date10 Jun, 2012

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 10 Jun, 2012 Chopped
B 10 Jun, 2012 Chopped
C 10 Jun, 2012 Chopped
D 10 Jun, 2012 Chopped
E 10 Jun, 2012 Chopped
F 10 Jun, 2012 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4aq3A00 26 Jul, 2013 Holding pen
4aq3B00 26 Jul, 2013 Holding pen
4aq3C00 26 Jul, 2013 Holding pen
4aq3D00 26 Jul, 2013 Holding pen
4aq3E00 26 Jul, 2013 Holding pen
4aq3F00 26 Jul, 2013 Holding pen

UniProtKB Entries (12)

Accession Gene ID Taxon Description
P10415 BCL2_HUMAN Homo sapiens Apoptosis regulator Bcl-2
P10415 BCL2_HUMAN Homo sapiens Apoptosis regulator Bcl-2
P10415 BCL2_HUMAN Homo sapiens Apoptosis regulator Bcl-2
P10415 BCL2_HUMAN Homo sapiens Apoptosis regulator Bcl-2
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
P10415 BCL2_HUMAN Homo sapiens Apoptosis regulator Bcl-2
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
P10415 BCL2_HUMAN Homo sapiens Apoptosis regulator Bcl-2
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1