PDB 4ajp

PDB Information

PDB4AJP
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation
Ward, R., Brassington, C., Breeze, A.L., Caputo, A., Critchlow, S., Davies, G., Goodwin, L., Hassall, G., Greenwood, R., Holdgate, G., Mrosek, M., Norman, R.A., Pearson, S., Tart, J., Tucker, J.A., Vogtherr, M., Whittaker, D., Wingfield, J., Winter, J., Hudson, K.
J.Med.Chem.
HeaderOxidoreductase/Inhibitor
Released2012-02-16
Resolution2.380
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4ajpA01 01 Feb, 2013 3.40.50.720 Assigned
4ajpA02 01 Feb, 2013 3.90.110.10 Assigned
4ajpB01 01 Feb, 2013 3.40.50.720 Assigned
4ajpB02 01 Feb, 2013 3.90.110.10 Assigned
4ajpC01 01 Feb, 2013 3.40.50.720 Assigned
4ajpC02 01 Feb, 2013 3.90.110.10 Assigned
4ajpD01 01 Feb, 2013 3.40.50.720 Assigned
4ajpD02 01 Feb, 2013 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
CATH-Gene3D is a Global Biodata Core Resource Learn more...