PDB 4ajo

PDB Information

PDB4AJO
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceRATTUS NORVEGICUS
Primary Citation
The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation
Ward, R., Brassington, C., Breeze, A.L., Caputo, A., Critchlow, S., Davies, G., Goodwin, L., Hassall, G., Greenwood, R., Holdgate, G., Mrosek, M., Norman, R.A., Pearson, S., Tart, J., Tucker, J.A., Vogtherr, M., Whittaker, D., Wingfield, J., Winter, J., Hudson, K.
J.Med.Chem.
HeaderOxidoreductase/Inhibitor
Released2012-02-16
Resolution1.960
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4ajoA01 01 Feb, 2013 3.40.50.720 Assigned
4ajoA02 01 Feb, 2013 3.90.110.10 Assigned
4ajoB01 01 Feb, 2013 3.40.50.720 Assigned
4ajoB02 01 Feb, 2013 3.90.110.10 Assigned
4ajoC01 01 Feb, 2013 3.40.50.720 Assigned
4ajoC02 01 Feb, 2013 3.90.110.10 Assigned
4ajoD01 01 Feb, 2013 3.40.50.720 Assigned
4ajoD02 01 Feb, 2013 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain