PDB 4ajk

PDB Information

PDB4AJK
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceRATTUS NORVEGICUS
Primary Citation
The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation
Ward, R., Brassington, C., Breeze, A.L., Caputo, A., Critchlow, S., Davies, G., Goodwin, L., Hassall, G., Greenwood, R., Holdgate, G., Mrosek, M., Norman, R.A., Pearson, S., Tart, J., Tucker, J.A., Vogtherr, M., Whittaker, D., Wingfield, J., Winter, J., Hudson, K.
J.Med.Chem.
HeaderOxidoreductase/Inhibitor
Released2012-02-16
Resolution2.030
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4ajkA01 01 Feb, 2013 3.40.50.720 Assigned
4ajkA02 01 Feb, 2013 3.90.110.10 Assigned
4ajkB01 01 Feb, 2013 3.40.50.720 Assigned
4ajkB02 01 Feb, 2013 3.90.110.10 Assigned
4ajkC01 01 Feb, 2013 3.40.50.720 Assigned
4ajkC02 01 Feb, 2013 3.90.110.10 Assigned
4ajkD01 01 Feb, 2013 3.40.50.720 Assigned
4ajkD02 01 Feb, 2013 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
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