×
Network disruptions
We have been experiencing disruptions on our local network which has affected the stability of these web pages.
We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.
PDB Information
| PDB | 4AF3 |
| Method | X-RAY DIFFRACTION |
| Host Organism | ESCHERICHIA COLI |
| Gene Source | HOMO SAPIENS |
| Primary Citation |
Crystal Structure of Human Aurora B in Complex with Incenp and Vx-680.
Elkins, J.M., Santaguida, S., Musacchio, A., Knapp, S.
J.Med.Chem.
|
| Header | Transferase/Inhibitor |
| Released | 2012-01-16 |
| Resolution | 2.750 |
| CATH Insert Date | 27 May, 2012 |
PDB Images (6)
4af3A01
CATH Domain 4af3A01
4af3A02
CATH Domain 4af3A02
4af3D01
CATH Domain 4af3D01
PDB Chains (2)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 28 May, 2012 | Chopped
|
| D | 28 May, 2012 | Chopped
|
CATH Domains (3)
UniProtKB Entries (2)
| Accession |
Gene ID |
Taxon |
Description |
| Q9NQS7 |
INCE_HUMAN |
Homo sapiens |
Inner centromere protein |
| Q96GD4 |
AURKB_HUMAN |
Homo sapiens |
Aurora kinase B |