PDB 4ael

PDB Links
Overview

PDB Information

PDB	4AEL
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Discovery of 4-Hydroxy-1,6-Naphthyridine-3-Carbonitrile Derivatives as Novel Pde10A Inhibitors. Bauer, U., Giordanetto, F., Bauer, M., O'Mahony, G., Johansson, K.E., Knecht, W., Hartleib-Geschwindner, J., Carlsson, E.T., Enroth, C. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2012-01-11
Resolution	2.200
CATH Insert Date	29 Jan, 2012

PDB Images (5)

Image of CATH 4ael

4ael

PDB 4ael

Image of CATH 4aelA

4aelA

PDB Chain 4aelA

Image of CATH 4aelB

4aelB

PDB Chain 4aelB

Image of CATH 4aelA00

4aelA00

CATH Domain 4aelA00

Image of CATH 4aelB00

4aelB00

CATH Domain 4aelB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	30 Jan, 2012	Chopped
B	30 Jan, 2012	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4aelA00	08 Feb, 2013	1.10.1300.10	Assigned
4aelB00	08 Feb, 2013	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A