PDB 3zc6

PDB Information

PDB3ZC6
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Strategic Use of Conformational Bias and Structure Based Design to Identify Potent Jak3 Inhibitors with Improved Selectivity Against the Jak Family and the Kinome.
Lynch, S.M., Devicente, J., Hermann, J.C., Jaime-Figueroa, S., Jin, S., Kuglstatter, A., Li, H., Lovey, A., Menke, J., Niu, L., Patel, V., Roy, D., Soth, M., Steiner, S., Tivitmahaisoon, P., Vu, M.D., Yee, C.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2012-11-16
Resolution2.420
CATH Insert Date06 Oct, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 07 Oct, 2013 Chopped
B 07 Oct, 2013 Chopped
C 07 Oct, 2013 Chopped
D 07 Oct, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3zc6A01 10 Oct, 2013 3.30.200.20 Assigned
3zc6A02 10 Oct, 2013 1.10.510.10 Assigned
3zc6B01 10 Oct, 2013 3.30.200.20 Assigned
3zc6B02 10 Oct, 2013 1.10.510.10 Assigned
3zc6C01 10 Oct, 2013 3.30.200.20 Assigned
3zc6C02 10 Oct, 2013 1.10.510.10 Assigned
3zc6D01 10 Oct, 2013 3.30.200.20 Assigned
3zc6D02 10 Oct, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
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