PDB Information

PDB3WJL
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Engineered antibody Fc variant with selectively enhanced Fc gamma RIIb binding over both Fc gamma RIIaR131 and Fc gamma RIIaH131.
Mimoto, F., Katada, H., Kadono, S., Igawa, T., Kuramochi, T., Muraoka, M., Wada, Y., Haraya, K., Miyazaki, T., Hattori, K.
Protein Eng.Des.Sel.
HeaderImmune System
Released2013-10-11
Resolution2.860
CATH Insert Date17 Nov, 2013

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 18 Nov, 2013 Chopped
B 18 Nov, 2013 Chopped
C 18 Nov, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3wjlA01 20 Nov, 2013 2.60.40.10 Assigned
3wjlA02 20 Nov, 2013 2.60.40.10 Assigned
3wjlB01 20 Nov, 2013 2.60.40.10 Assigned
3wjlB02 20 Nov, 2013 2.60.40.10 Assigned
3wjlC01 20 Nov, 2013 2.60.40.10 Assigned
3wjlC02 20 Nov, 2013 2.60.40.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P31995 FCG2C_HUMAN Homo sapiens Low affinity immunoglobulin gamma Fc region receptor II-c
P01857 IGHG1_HUMAN Homo sapiens Immunoglobulin heavy constant gamma 1
P01857 IGHG1_HUMAN Homo sapiens Immunoglobulin heavy constant gamma 1