PDB 3wix

PDB Links
Overview

PDB Information

PDB	3WIX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins. Tanaka, Y., Aikawa, K., Nishida, G., Homma, M., Sogabe, S., Igaki, S., Hayano, Y., Sameshima, T., Miyahisa, I., Kawamoto, T., Tawada, M., Imai, Y., Inazuka, M., Cho, N., Imaeda, Y., Ishikawa, T. J.Med.Chem.
Header	Apoptosis
Released	2013-09-26
Resolution	1.900
CATH Insert Date	01 Dec, 2013

PDB Images (9)

Image of CATH 3wix

3wix

PDB 3wix

Image of CATH 3wixA

3wixA

PDB Chain 3wixA

Image of CATH 3wixB

3wixB

PDB Chain 3wixB

Image of CATH 3wixC

3wixC

PDB Chain 3wixC

Image of CATH 3wixD

3wixD

PDB Chain 3wixD

Image of CATH 3wixA01

3wixA01

CATH Domain 3wixA01

Image of CATH 3wixB01

3wixB01

CATH Domain 3wixB01

Image of CATH 3wixC01

3wixC01

CATH Domain 3wixC01

Image of CATH 3wixD01

3wixD01

CATH Domain 3wixD01

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	02 Dec, 2013	Chopped
B	02 Dec, 2013	Chopped
C	02 Dec, 2013	Chopped
D	02 Dec, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3wixA01	04 Dec, 2013	1.10.437.10	Assigned
3wixB01	04 Dec, 2013	1.10.437.10	Assigned
3wixC01	04 Dec, 2013	1.10.437.10	Assigned
3wixD01	04 Dec, 2013	1.10.437.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1