PDB 3wig

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PDB Links
Overview

PDB Information

PDB	3WIG
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors Lito, P., Saborowski, A., Yue, J., Solomon, M., Joseph, E., Gadal, S., Saborowski, M., Kastenhuber, E., Fellmann, C., Ohara, K., Morikami, K., Miura, T., Lukacs, C., Ishii, N., Lowe, S., Rosen, N. Cancer Cell
Header	Transferase/Transferase Inhibitor
Released	2013-09-12
Resolution	2.700
CATH Insert Date	15 Jun, 2014

PDB Images (4)

Image of CATH 3wig

3wig

PDB 3wig

Image of CATH 3wigA

3wigA

PDB Chain 3wigA

Image of CATH 3wigA01

3wigA01

CATH Domain 3wigA01

Image of CATH 3wigA02

3wigA02

CATH Domain 3wigA02

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	16 Jun, 2014	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3wigA01	18 Jun, 2014	3.30.200.20	Assigned
3wigA02	18 Jun, 2014	1.10.510.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q02750	MP2K1_HUMAN	Homo sapiens	Dual specificity mitogen-activated protein kinase kinase 1