PDB 3wi2

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Overview

PDB Information

PDB	3WI2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition. Hamaguchi, W., Masuda, N., Isomura, M., Miyamoto, S., Kikuchi, S., Amano, Y., Honbou, K., Mihara, T., Watanabe, T. Bioorg.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-09-04
Resolution	2.260
CATH Insert Date	15 Dec, 2013

PDB Images (5)

Image of CATH 3wi2

3wi2

PDB 3wi2

Image of CATH 3wi2A

3wi2A

PDB Chain 3wi2A

Image of CATH 3wi2B

3wi2B

PDB Chain 3wi2B

Image of CATH 3wi2A00

3wi2A00

CATH Domain 3wi2A00

Image of CATH 3wi2B00

3wi2B00

CATH Domain 3wi2B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2013	Chopped
B	16 Dec, 2013	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3wi2A00	20 Dec, 2013	1.10.1300.10	Assigned
3wi2B00	20 Dec, 2013	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A