PDB Information

PDB3VSX
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isopropylhexanamides as renin inhibitors
Nakamura, Y., Sugita, C., Meguro, M., Miyazaki, S., Tamaki, K., Takahashi, M., Nagai, Y., Nagayama, T., Kato, M., Suemune, H., Nishi, T.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-05-11
Resolution2.800
CATH Insert Date04 Nov, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3vsxA01 04 Nov, 2013 2.40.70.10 Assigned
3vsxA02 04 Nov, 2013 2.40.70.10 Assigned
3vsxB01 04 Nov, 2013 2.40.70.10 Assigned
3vsxB02 04 Nov, 2013 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin