PDB Information

PDB3VF5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 (BRU ISOLATE)
Primary Citation
Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.
Chang, Y.C., Yu, X., Zhang, Y., Tie, Y., Wang, Y.F., Yashchuk, S., Ghosh, A.K., Harrison, R.W., Weber, I.T.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-01-09
Resolution1.250
CATH Insert Date02 Dec, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 31 Dec, 2012 Chopped
B 31 Dec, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3vf5A00 03 Jan, 2013 2.40.70.10 Assigned
3vf5B00 03 Jan, 2013 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03367 POL_HV1BR Human immunodeficiency virus type 1 (BRU ISOLATE) Gag-Pol polyprotein
P03367 POL_HV1BR Human immunodeficiency virus type 1 (BRU ISOLATE) Gag-Pol polyprotein