PDB 3v8w

PDB Links
Overview

PDB Information

PDB	3V8W
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase. McLean, L.R., Zhang, Y., Zaidi, N., Bi, X., Wang, R., Dharanipragada, R., Jurcak, J.G., Gillespy, T.A., Zhao, Z., Musick, K.Y., Choi, Y.M., Barrague, M., Peppard, J., Smicker, M., Duguid, M., Parkar, A., Fordham, J., Kominos, D. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2011-12-23
Resolution	2.270
CATH Insert Date	27 May, 2012

PDB Images (7)

Image of CATH 3v8w

3v8w

PDB 3v8w

Image of CATH 3v8wA

3v8wA

PDB Chain 3v8wA

Image of CATH 3v8wB

3v8wB

PDB Chain 3v8wB

Image of CATH 3v8wA01

3v8wA01

CATH Domain 3v8wA01

Image of CATH 3v8wA02

3v8wA02

CATH Domain 3v8wA02

Image of CATH 3v8wB01

3v8wB01

CATH Domain 3v8wB01

Image of CATH 3v8wB02

3v8wB02

CATH Domain 3v8wB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 May, 2012	Chopped
B	28 May, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3v8wA01	08 Jun, 2012	3.30.200.20	Assigned
3v8wA02	08 Jun, 2012	1.10.510.10	Assigned
3v8wB01	08 Jun, 2012	3.30.200.20	Assigned
3v8wB02	08 Jun, 2012	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q08881	ITK_HUMAN	Homo sapiens	Tyrosine-protein kinase ITK/TSK
Q08881	ITK_HUMAN	Homo sapiens	Tyrosine-protein kinase ITK/TSK