PDB Information

PDB3V6S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of potent and selective covalent inhibitors of JNK.
Zhang, T., Inesta-Vaquera, F., Niepel, M., Zhang, J., Ficarro, S.B., Machleidt, T., Xie, T., Marto, J.A., Kim, N., Sim, T., Laughlin, J.D., Park, H., LoGrasso, P.V., Patricelli, M., Nomanbhoy, T.K., Sorger, P.K., Alessi, D.R., Gray, N.S.
Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2011-12-20
Resolution2.970
CATH Insert Date05 Feb, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Feb, 2012 Chopped
B 06 Feb, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3v6sA01 09 Feb, 2012 3.30.200.20 Assigned
3v6sA02 09 Feb, 2012 1.10.510.10 Assigned
3v6sB01 09 Feb, 2012 3.30.200.20 Assigned
3v6sB02 09 Feb, 2012 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P53779 MK10_HUMAN Homo sapiens Mitogen-activated protein kinase 10
P53779 MK10_HUMAN Homo sapiens Mitogen-activated protein kinase 10