PDB Information

PDB3V5W
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility.
Thal, D.M., Homan, K.T., Chen, J., Wu, E.K., Hinkle, P.M., Huang, Z.M., Chuprun, J.K., Song, J., Gao, E., Cheung, J.Y., Sklar, L.A., Koch, W.J., Tesmer, J.J.
Acs Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2011-12-17
Resolution2.070
CATH Insert Date04 Nov, 2012

PDB Images (11)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
G 05 Nov, 2012 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
3v5wA01 10 Nov, 2012 New
3v5wA02 10 Nov, 2012 1.10.167.10 Assigned
3v5wA03 10 Nov, 2012 3.30.200.20 Assigned
3v5wA04 10 Nov, 2012 1.10.510.10 Assigned
3v5wA05 10 Nov, 2012 2.30.29.30 Assigned
3v5wB00 10 Nov, 2012 2.130.10.10 Assigned
3v5wG00 10 Nov, 2012 4.10.260.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P63212 GBG2_BOVIN Bos taurus Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
P62871 GBB1_BOVIN Bos taurus Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
P25098 ARBK1_HUMAN Homo sapiens Beta-adrenergic receptor kinase 1