PDB 3v5l

PDB Information

PDB3V5L
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.
McLean, L.R., Zhang, Y., Zaidi, N., Bi, X., Wang, R., Dharanipragada, R., Jurcak, J.G., Gillespy, T.A., Zhao, Z., Musick, K.Y., Choi, Y.M., Barrague, M., Peppard, J., Smicker, M., Duguid, M., Parkar, A., Fordham, J., Kominos, D.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-12-16
Resolution1.860
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3v5lA01 08 Jun, 2012 3.30.200.20 Assigned
3v5lA02 08 Jun, 2012 1.10.510.10 Assigned
3v5lB01 08 Jun, 2012 3.30.200.20 Assigned
3v5lB02 08 Jun, 2012 1.10.510.10 Assigned
3v5lC01 08 Jun, 2012 3.30.200.20 Assigned
3v5lC02 08 Jun, 2012 1.10.510.10 Assigned
3v5lD01 08 Jun, 2012 3.30.200.20 Assigned
3v5lD02 08 Jun, 2012 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
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