PDB 3um8

PDB Information

PDB3UM8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil.
Vanichtanankul, J., Taweechai, S., Uttamapinant, C., Chitnumsub, P., Vilaivan, T., Yuthavong, Y., Kamchonwongpaisan, S.
Antimicrob.Agents Chemother.
HeaderOxidoreductase, Transferase/Inhibitor
Released2011-11-12
Resolution2.600
CATH Insert Date04 Nov, 2012

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3um8A01 30 Aug, 2013 3.40.430.10 Assigned
3um8A02 30 Aug, 2013 6.10.250.2210 Assigned
3um8A03 30 Aug, 2013 3.30.572.10 Assigned
3um8B01 30 Aug, 2013 3.40.430.10 Assigned
3um8B02 30 Aug, 2013 6.10.250.2210 Assigned
3um8B03 30 Aug, 2013 3.30.572.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
A7UD81 A7UD81_PLAFA Plasmodium falciparum Bifunctional dihydrofolate reductase-thymidylate synthase
A7UD81 A7UD81_PLAFA Plasmodium falciparum Bifunctional dihydrofolate reductase-thymidylate synthase