PDB 3ui7

PDB Links
Overview

PDB Information

PDB	3UI7
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia. Yang, S.W., Smotryski, J., McElroy, W.T., Tan, Z., Ho, G., Tulshian, D., Greenlee, W.J., Guzzi, M., Zhang, X., Mullins, D., Xiao, L., Hruza, A., Chan, T.M., Rindgen, D., Bleickardt, C., Hodgson, R. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2011-11-04
Resolution	2.280
CATH Insert Date	08 Jan, 2012

PDB Images (5)

Image of CATH 3ui7

3ui7

PDB 3ui7

Image of CATH 3ui7A

3ui7A

PDB Chain 3ui7A

Image of CATH 3ui7B

3ui7B

PDB Chain 3ui7B

Image of CATH 3ui7A00

3ui7A00

CATH Domain 3ui7A00

Image of CATH 3ui7B00

3ui7B00

CATH Domain 3ui7B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	09 Jan, 2012	Chopped
B	09 Jan, 2012	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3ui7A00	08 Feb, 2013	1.10.1300.10	Assigned
3ui7B00	08 Feb, 2013	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A