PDB 3ue8

PDB Links
Overview

PDB Information

PDB	3UE8
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia. Dounay, A.B., Anderson, M., Bechle, B.M., Campbell, B.M., Claffey, M.M., Evdokimov, A., Evrard, E., Fonseca, K.R., Gan, X., Ghosh, S., Hayward, M.M., Horner, W., Kim, J.Y., McAllister, L.A., Pandit, J., Paradis, V., Parikh, V.D., Reese, M.R., Rong, S., Salafia, M.A., Schuyten, K., Strick, C.A., Tuttle, J.B., Valentine, J., Wang, H., Zawadzke, L.E., Verhoest, P.R. ACS Med Chem Lett
Header	Transferase/Transferase Inhibitor
Released	2011-10-28
Resolution	3.220
CATH Insert Date	05 Feb, 2012

PDB Images (9)

Image of CATH 3ue8

3ue8

PDB 3ue8

Image of CATH 3ue8A

3ue8A

PDB Chain 3ue8A

Image of CATH 3ue8B

3ue8B

PDB Chain 3ue8B

Image of CATH 3ue8A01

3ue8A01

CATH Domain 3ue8A01

Image of CATH 3ue8A02

3ue8A02

CATH Domain 3ue8A02

Image of CATH 3ue8A03

3ue8A03

CATH Domain 3ue8A03

Image of CATH 3ue8B01

3ue8B01

CATH Domain 3ue8B01

Image of CATH 3ue8B02

3ue8B02

CATH Domain 3ue8B02

Image of CATH 3ue8B03

3ue8B03

CATH Domain 3ue8B03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	06 Feb, 2012	Chopped
B	06 Feb, 2012	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3ue8A01	30 Aug, 2013		Holding pen
3ue8A02	30 Aug, 2013	3.40.640.10	Assigned
3ue8A03	30 Aug, 2013	3.90.1150.10	Assigned
3ue8B01	30 Aug, 2013		Holding pen
3ue8B02	30 Aug, 2013	3.40.640.10	Assigned
3ue8B03	30 Aug, 2013	3.90.1150.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8N5Z0	AADAT_HUMAN	Homo sapiens	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Q8N5Z0	AADAT_HUMAN	Homo sapiens	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial