PDB 3udd

PDB Information

PDB3UDD
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
[1,2,4]triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: antagonists of the Wnt pathway that inhibit tankyrases 1 and 2 via novel adenosine pocket binding.
Shultz, M.D., Kirby, C.A., Stams, T., Chin, D.N., Blank, J., Charlat, O., Cheng, H., Cheung, A., Cong, F., Feng, Y., Fortin, P.D., Hood, T., Tyagi, V., Xu, M., Zhang, B., Shao, W.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-10-28
Resolution1.950
CATH Insert Date05 Feb, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Feb, 2012 Chopped
B 06 Feb, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3uddA00 09 Feb, 2012 3.90.228.10 Assigned
3uddB00 09 Feb, 2012 3.90.228.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O95271 TNKS1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-1
O95271 TNKS1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-1
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