PDB 3u6a

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Overview

PDB Information

PDB	3U6A
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Rational design and synthesis of aminopiperazinones as beta-secretase (BACE) inhibitors. Tresadern, G., Delgado, F., Delgado, O., Gijsen, H., Macdonald, G.J., Moechars, D., Rombouts, F., Alexander, R., Spurlino, J., Van Gool, M., Vega, J.A., Trabanco, A.A. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2011-10-12
Resolution	2.200
CATH Insert Date	13 Nov, 2011

PDB Images (10)

Image of CATH 3u6a

3u6a

PDB 3u6a

Image of CATH 3u6aA

3u6aA

PDB Chain 3u6aA

Image of CATH 3u6aB

3u6aB

PDB Chain 3u6aB

Image of CATH 3u6aC

3u6aC

PDB Chain 3u6aC

Image of CATH 3u6aA01

3u6aA01

CATH Domain 3u6aA01

Image of CATH 3u6aA02

3u6aA02

CATH Domain 3u6aA02

Image of CATH 3u6aB01

3u6aB01

CATH Domain 3u6aB01

Image of CATH 3u6aB02

3u6aB02

CATH Domain 3u6aB02

Image of CATH 3u6aC01

3u6aC01

CATH Domain 3u6aC01

Image of CATH 3u6aC02

3u6aC02

CATH Domain 3u6aC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	29 Nov, 2011	Chopped
B	29 Nov, 2011	Chopped
C	29 Nov, 2011	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3u6aA01	01 Dec, 2011	2.40.70.10	Assigned
3u6aA02	01 Dec, 2011	2.40.70.10	Assigned
3u6aB01	01 Dec, 2011	2.40.70.10	Assigned
3u6aB02	01 Dec, 2011	2.40.70.10	Assigned
3u6aC01	01 Dec, 2011	2.40.70.10	Assigned
3u6aC02	01 Dec, 2011	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1