PDB Information

PDB3U4O
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides.
Anilkumar, G.N., Selyutin, O., Rosenblum, S.B., Zeng, Q., Jiang, Y., Chan, T.Y., Pu, H., Wang, L., Bennett, F., Chen, K.X., Lesburg, C.A., Duca, J., Gavalas, S., Huang, Y., Pinto, P., Sannigrahi, M., Velazquez, F., Venkatraman, S., Vibulbhan, B., Agrawal, S., Ferrari, E., Jiang, C.K., Huang, H.C., Shih, N.Y., George Njoroge, F., Kozlowski, J.A.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-10-10
Resolution1.770
CATH Insert Date11 Dec, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 12 Dec, 2011 Chopped
B 12 Dec, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3u4oA01 08 Oct, 2013 Holding pen
3u4oA02 08 Oct, 2013 Holding pen
3u4oB01 08 Oct, 2013 Holding pen
3u4oB02 08 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein