PDB 3tik

PDB Links
Overview

PDB Information

PDB	3TIK
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Trypanosoma brucei
Primary Citation	Pharmacological characterization, structural studies, and in vivo activities of anti-chagas disease lead compounds derived from tipifarnib. Buckner, F.S., Bahia, M.T., Suryadevara, P.K., White, K.L., Shackleford, D.M., Chennamaneni, N.K., Hulverson, M.A., Laydbak, J.U., Chatelain, E., Scandale, I., Verlinde, C.L., Charman, S.A., Lepesheva, G.I., Gelb, M.H. Antimicrob.Agents Chemother.
Header	Oxidoreductase
Released	2011-08-20
Resolution	2.050
CATH Insert Date	04 Nov, 2012

PDB Images (9)

Image of CATH 3tik

3tik

PDB 3tik

Image of CATH 3tikA

3tikA

PDB Chain 3tikA

Image of CATH 3tikB

3tikB

PDB Chain 3tikB

Image of CATH 3tikC

3tikC

PDB Chain 3tikC

Image of CATH 3tikD

3tikD

PDB Chain 3tikD

Image of CATH 3tikA00

3tikA00

CATH Domain 3tikA00

Image of CATH 3tikB00

3tikB00

CATH Domain 3tikB00

Image of CATH 3tikC00

3tikC00

CATH Domain 3tikC00

Image of CATH 3tikD00

3tikD00

CATH Domain 3tikD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped
C	05 Nov, 2012	Chopped
D	05 Nov, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3tikA00	10 Nov, 2012	1.10.630.10	Assigned
3tikB00	10 Nov, 2012	1.10.630.10	Assigned
3tikC00	10 Nov, 2012	1.10.630.10	Assigned
3tikD00	10 Nov, 2012	1.10.630.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase