PDB 3t3p

PDB Information

PDB3T3P
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS
Zhu, J., Choi, W.S., McCoy, J.G., Negri, A., Zhu, J., Naini, S., Li, J., Shen, M., Huang, W., Bougie, D., Rasmussen, M., Aster, R., Thomas, C.J., Filizola, M., Springer, T.A., Coller, B.S.
Sci Transl Med
HeaderCell Adhesion
Released2011-07-25
Resolution2.200
CATH Insert Date27 May, 2012

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped
E 28 May, 2012 Chopped
F 28 May, 2012 Chopped
H 28 May, 2012 Chopped
L 28 May, 2012 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
3t3pA00 08 Jun, 2012 2.130.10.130 Assigned
3t3pB01 04 Jul, 2013 3.30.1680.10 Assigned
3t3pB02 04 Jul, 2013 2.60.40.1510 Assigned
3t3pB03 04 Jul, 2013 3.40.50.410 Assigned
3t3pC00 08 Jun, 2012 2.130.10.130 Assigned
3t3pD01 04 Jul, 2013 3.30.1680.10 Assigned
3t3pD02 04 Jul, 2013 2.60.40.1510 Assigned
3t3pD03 04 Jul, 2013 3.40.50.410 Assigned
3t3pE01 08 Jun, 2012 2.60.40.10 Assigned
3t3pE02 08 Jun, 2012 2.60.40.10 Assigned
3t3pF01 08 Jun, 2012 2.60.40.10 Assigned
3t3pF02 08 Jun, 2012 2.60.40.10 Assigned
3t3pH01 08 Jun, 2012 2.60.40.10 Assigned
3t3pH02 08 Jun, 2012 2.60.40.10 Assigned
3t3pL01 08 Jun, 2012 2.60.40.10 Assigned
3t3pL02 08 Jun, 2012 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P08514 ITA2B_HUMAN Homo sapiens Integrin alpha-IIb
P08514 ITA2B_HUMAN Homo sapiens Integrin alpha-IIb
P05106 ITB3_HUMAN Homo sapiens Integrin beta-3
P05106 ITB3_HUMAN Homo sapiens Integrin beta-3
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