PDB 3t3m

PDB Information

PDB3T3M
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS
Zhu, J., Choi, W.S., McCoy, J.G., Negri, A., Zhu, J., Naini, S., Li, J., Shen, M., Huang, W., Bougie, D., Rasmussen, M., Aster, R., Thomas, C.J., Filizola, M., Springer, T.A., Coller, B.S.
Sci Transl Med
HeaderCell Adhesion
Released2011-07-25
Resolution2.600
CATH Insert Date27 May, 2012

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped
E 28 May, 2012 Chopped
F 28 May, 2012 Chopped
H 28 May, 2012 Chopped
L 28 May, 2012 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
3t3mA00 08 Jun, 2012 2.130.10.130 Assigned
3t3mB01 04 Jul, 2013 3.30.1680.10 Assigned
3t3mB02 04 Jul, 2013 2.60.40.1510 Assigned
3t3mB03 04 Jul, 2013 3.40.50.410 Assigned
3t3mC00 08 Jun, 2012 2.130.10.130 Assigned
3t3mD01 04 Jul, 2013 3.30.1680.10 Assigned
3t3mD02 04 Jul, 2013 2.60.40.1510 Assigned
3t3mD03 04 Jul, 2013 3.40.50.410 Assigned
3t3mE01 08 Jun, 2012 2.60.40.10 Assigned
3t3mE02 08 Jun, 2012 2.60.40.10 Assigned
3t3mF01 08 Jun, 2012 2.60.40.10 Assigned
3t3mF02 08 Jun, 2012 2.60.40.10 Assigned
3t3mH01 08 Jun, 2012 2.60.40.10 Assigned
3t3mH02 08 Jun, 2012 2.60.40.10 Assigned
3t3mL01 08 Jun, 2012 2.60.40.10 Assigned
3t3mL02 08 Jun, 2012 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P08514 ITA2B_HUMAN Homo sapiens Integrin alpha-IIb
P05106 ITB3_HUMAN Homo sapiens Integrin beta-3
P05106 ITB3_HUMAN Homo sapiens Integrin beta-3
P08514 ITA2B_HUMAN Homo sapiens Integrin alpha-IIb