PDB 3t0t

PDB Information

PDB3T0T
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus subsp. aureus
Primary Citation
Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase.
Axerio-Cilies, P., See, R.H., Zoraghi, R., Worral, L., Lian, T., Stoynov, N., Jiang, J., Kaur, S., Jackson, L., Gong, H., Swayze, R., Amandoron, E., Kumar, N.S., Moreau, A., Hsing, M., Strynadka, N.C., McMaster, W.R., Finlay, B.B., Foster, L.J., Young, R.N., Reiner, N.E., Cherkasov, A.
Acs Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2011-07-20
Resolution3.100
CATH Insert Date10 Jun, 2012

PDB Images (21)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 10 Jun, 2012 Chopped
B 10 Jun, 2012 Chopped
C 10 Jun, 2012 Chopped
D 10 Jun, 2012 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
3t0tA01 20 Jun, 2012 3.20.20.60 Assigned
3t0tA02 20 Jun, 2012 2.40.33.10 Assigned
3t0tA03 20 Jun, 2012 3.40.1380.20 Assigned
3t0tA04 20 Jun, 2012 3.50.30.10 Assigned
3t0tB01 20 Jun, 2012 3.20.20.60 Assigned
3t0tB02 20 Jun, 2012 2.40.33.10 Assigned
3t0tB03 20 Jun, 2012 3.40.1380.20 Assigned
3t0tB04 20 Jun, 2012 3.50.30.10 Assigned
3t0tC01 20 Jun, 2012 3.20.20.60 Assigned
3t0tC02 20 Jun, 2012 2.40.33.10 Assigned
3t0tC03 20 Jun, 2012 3.40.1380.20 Assigned
3t0tC04 20 Jun, 2012 3.50.30.10 Assigned
3t0tD01 20 Jun, 2012 3.20.20.60 Assigned
3t0tD02 20 Jun, 2012 2.40.33.10 Assigned
3t0tD03 20 Jun, 2012 3.40.1380.20 Assigned
3t0tD04 20 Jun, 2012 3.50.30.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q6GG09 KPYK_STAAR Staphylococcus aureus subsp. aureus MRSA252 Pyruvate kinase
Q6GG09 KPYK_STAAR Staphylococcus aureus subsp. aureus MRSA252 Pyruvate kinase
Q6GG09 KPYK_STAAR Staphylococcus aureus subsp. aureus MRSA252 Pyruvate kinase
Q6GG09 KPYK_STAAR Staphylococcus aureus subsp. aureus MRSA252 Pyruvate kinase
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