PDB 3sww

PDB Links
Overview

PDB Information

PDB	3SWW
Method	X-RAY DIFFRACTION
Host Organism	Pichia pastoris
Gene Source	Homo sapiens
Primary Citation	7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site. Wang, W., Devasthale, P., Wang, A., Harrity, T., Egan, D., Morgan, N., Cap, M., Fura, A., Klei, H.E., Kish, K., Weigelt, C., Sun, L., Levesque, P., Li, Y.X., Zahler, R., Kirby, M.S., Hamann, L.G. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2011-07-14
Resolution	2.000
CATH Insert Date	30 Oct, 2011

PDB Images (7)

Image of CATH 3sww

3sww

PDB 3sww

Image of CATH 3swwA

3swwA

PDB Chain 3swwA

Image of CATH 3swwB

3swwB

PDB Chain 3swwB

Image of CATH 3swwA01

3swwA01

CATH Domain 3swwA01

Image of CATH 3swwA02

3swwA02

CATH Domain 3swwA02

Image of CATH 3swwB01

3swwB01

CATH Domain 3swwB01

Image of CATH 3swwB02

3swwB02

CATH Domain 3swwB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Nov, 2011	Chopped
B	29 Nov, 2011	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3swwA01	01 Dec, 2011	3.40.50.1820	Assigned
3swwA02	01 Dec, 2011	2.140.10.30	Assigned
3swwB01	01 Dec, 2011	3.40.50.1820	Assigned
3swwB02	01 Dec, 2011	2.140.10.30	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4