PDB 3sqo

PDB Information

PDB3SQO
MethodX-RAY DIFFRACTION
Host Organismhomo sapiens
Gene SourceHomo sapiens
Primary Citation
Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates.
Liang, H., Chaparro-Riggers, J., Strop, P., Geng, T., Sutton, J.E., Tsai, D., Bai, L., Abdiche, Y., Dilley, J., Yu, J., Wu, S., Chin, S.M., Lee, N.A., Rossi, A., Lin, J.C., Rajpal, A., Pons, J., Shelton, D.L.
J.Pharmacol.Exp.Ther.
HeaderHydrolase/Immune System
Released2011-07-05
Resolution2.700
CATH Insert Date27 May, 2012

PDB Images (12)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
H 28 May, 2012 Chopped
L 28 May, 2012 Chopped
P 28 May, 2012 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
3sqoA01 09 Oct, 2013 3.40.50.200 Assigned
3sqoA02 09 Oct, 2013 2.60.120.690 Assigned
3sqoH01 08 Jun, 2012 2.60.40.10 Assigned
3sqoH02 08 Jun, 2012 2.60.40.10 Assigned
3sqoL01 08 Jun, 2012 2.60.40.10 Assigned
3sqoL02 08 Jun, 2012 2.60.40.10 Assigned
3sqoP01 04 Feb, 2013 3.30.70.80 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9