PDB 3sl6

PDB Links
Overview

PDB Information

PDB	3SL6
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Nankervis, J.L., Feil, S.C., Hancock, N.C., Zheng, Z., Ng, H.L., Morton, C.J., Holien, J.K., Ho, P.W., Frazzetto, M.M., Jennings, I.G., Manallack, D.T., Martin, T.J., Thompson, P.E., Parker, M.W. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2011-06-24
Resolution	2.440
CATH Insert Date	30 Oct, 2011

PDB Images (9)

Image of CATH 3sl6

3sl6

PDB 3sl6

Image of CATH 3sl6A

3sl6A

PDB Chain 3sl6A

Image of CATH 3sl6B

3sl6B

PDB Chain 3sl6B

Image of CATH 3sl6C

3sl6C

PDB Chain 3sl6C

Image of CATH 3sl6D

3sl6D

PDB Chain 3sl6D

Image of CATH 3sl6A00

3sl6A00

CATH Domain 3sl6A00

Image of CATH 3sl6B00

3sl6B00

CATH Domain 3sl6B00

Image of CATH 3sl6C00

3sl6C00

CATH Domain 3sl6C00

Image of CATH 3sl6D00

3sl6D00

CATH Domain 3sl6D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	29 Nov, 2011	Chopped
B	29 Nov, 2011	Chopped
C	29 Nov, 2011	Chopped
D	29 Nov, 2011	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3sl6A00	25 Apr, 2013	1.10.1300.10	Assigned
3sl6B00	25 Apr, 2013	1.10.1300.10	Assigned
3sl6C00	25 Apr, 2013	1.10.1300.10	Assigned
3sl6D00	25 Apr, 2013	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D