PDB 3sl4

PDB Links
Overview

PDB Information

PDB	3SL4
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Nankervis, J.L., Feil, S.C., Hancock, N.C., Zheng, Z., Ng, H.L., Morton, C.J., Holien, J.K., Ho, P.W., Frazzetto, M.M., Jennings, I.G., Manallack, D.T., Martin, T.J., Thompson, P.E., Parker, M.W. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Inhibitor
Released	2011-06-24
Resolution	1.900
CATH Insert Date	30 Oct, 2011

PDB Images (9)

Image of CATH 3sl4

3sl4

PDB 3sl4

Image of CATH 3sl4A

3sl4A

PDB Chain 3sl4A

Image of CATH 3sl4B

3sl4B

PDB Chain 3sl4B

Image of CATH 3sl4C

3sl4C

PDB Chain 3sl4C

Image of CATH 3sl4D

3sl4D

PDB Chain 3sl4D

Image of CATH 3sl4A00

3sl4A00

CATH Domain 3sl4A00

Image of CATH 3sl4B00

3sl4B00

CATH Domain 3sl4B00

Image of CATH 3sl4C00

3sl4C00

CATH Domain 3sl4C00

Image of CATH 3sl4D00

3sl4D00

CATH Domain 3sl4D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	29 Nov, 2011	Chopped
B	29 Nov, 2011	Chopped
C	29 Nov, 2011	Chopped
D	29 Nov, 2011	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3sl4A00	25 Apr, 2013	1.10.1300.10	Assigned
3sl4B00	25 Apr, 2013	1.10.1300.10	Assigned
3sl4C00	25 Apr, 2013	1.10.1300.10	Assigned
3sl4D00	25 Apr, 2013	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D