PDB 3ske

PDB Information

PDB3SKE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus isolate HC-J4
Primary Citation
I. Novel HCV NS5B polymerase inhibitors: discovery of indole 2-carboxylic acids with C3-heterocycles.
Anilkumar, G.N., Lesburg, C.A., Selyutin, O., Rosenblum, S.B., Zeng, Q., Jiang, Y., Chan, T.Y., Pu, H., Vaccaro, H., Wang, L., Bennett, F., Chen, K.X., Duca, J., Gavalas, S., Huang, Y., Pinto, P., Sannigrahi, M., Velazquez, F., Venkatraman, S., Vibulbhan, B., Agrawal, S., Butkiewicz, N., Feld, B., Ferrari, E., He, Z., Jiang, C.K., Palermo, R.E., McMonagle, P., Huang, H.C., Shih, N.Y., Njoroge, G., Kozlowski, J.A.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-06-22
Resolution1.970
CATH Insert Date04 Sep, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2011 Chopped
B 05 Sep, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3skeA01 08 Oct, 2013 Holding pen
3skeA02 08 Oct, 2013 Holding pen
3skeB01 08 Oct, 2013 Holding pen
3skeB02 08 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein