PDB 3sdg

PDB Information

PDB3SDG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium tuberculosis
Primary Citation
Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors.
Flipo, M., Desroses, M., Lecat-Guillet, N., Villemagne, B., Blondiaux, N., Leroux, F., Piveteau, C., Mathys, V., Flament, M.P., Siepmann, J., Villeret, V., Wohlkonig, A., Wintjens, R., Soror, S.H., Christophe, T., Jeon, H.K., Locht, C., Brodin, P., Deprez, B., Baulard, A.R., Willand, N.
J.Med.Chem.
HeaderTranscription Repressor/Inhibitor
Released2011-06-09
Resolution1.870
CATH Insert Date11 Dec, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 12 Dec, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3sdgA01 16 Jan, 2012 1.10.10.60 Assigned
3sdgA02 16 Jan, 2012 1.10.357.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis H37Rv HTH-type transcriptional regulator EthR
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