PDB Information

PDB3SD5
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor.
Maira, S.M., Pecchi, S., Huang, A., Burger, M., Knapp, M., Sterker, D., Schnell, C., Guthy, D., Nagel, T., Wiesmann, M., Brachmann, S., Fritsch, C., Dorsch, M., Chene, P., Shoemaker, K., De Pover, A., Menezes, D., Martiny-Baron, G., Fabbro, D., Wilson, C.J., Schlegel, R., Hofmann, F., Garcia-Echeverria, C., Sellers, W.R., Voliva, C.F.
Mol.Cancer Ther.
HeaderTransferase/Transferase Inhibitor
Released2011-06-08
Resolution3.200
CATH Insert Date08 Jan, 2012

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 09 Jan, 2012 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3sd5A01 04 Sep, 2013 3.10.20.90 Assigned
3sd5A02 04 Sep, 2013 2.60.40.150 Assigned
3sd5A03 04 Sep, 2013 1.25.40.70 Assigned
3sd5A04 04 Sep, 2013 3.30.1010.10 Assigned
3sd5A05 04 Sep, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform