PDB Information

PDB3SC1
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery.
Johnson, M.C., Hu, Q., Lingardo, L., Ferre, R.A., Greasley, S., Yan, J., Kath, J., Chen, P., Ermolieff, J., Alton, G.
J Comput Aided Mol Des
HeaderTransferase/Transferase Inhibitor
Released2011-06-06
Resolution2.700
CATH Insert Date30 Oct, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3sc1A01 01 Dec, 2011 3.30.200.20 Assigned
3sc1A02 01 Dec, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O15530 PDPK1_HUMAN Homo sapiens 3-phosphoinositide-dependent protein kinase 1