PDB 3s7l

PDB Information

PDB3S7L
MethodX-RAY DIFFRACTION
Host OrganismEscherichia Coli
Gene SourceHomo sapiens
Primary Citation
New pyrazolyl and thienyl aminohydantoins as potent BACE1 inhibitors: Exploring the S2' region.
Malamas, M.S., Erdei, J., Gunawan, I., Barnes, K., Hui, Y., Johnson, M., Robichaud, A., Zhou, P., Yan, Y., Solvibile, W., Turner, J., Fan, K.Y., Chopra, R., Bard, J., Pangalos, M.N.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-05-26
Resolution2.160
CATH Insert Date04 Sep, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3s7lA01 07 Sep, 2011 2.40.70.10 Assigned
3s7lA02 07 Sep, 2011 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1