PDB Information

PDB3S2A
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure-Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives.
Nishimura, N., Siegmund, A., Liu, L., Yang, K., Bryan, M.C., Andrews, K.L., Bo, Y., Booker, S.K., Caenepeel, S., Freeman, D., Liao, H., McCarter, J., Mullady, E.L., San Miguel, T., Subramanian, R., Tamayo, N., Wang, L., Whittington, D.A., Zalameda, L., Zhang, N., Hughes, P.E., Norman, M.H.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-05-16
Resolution2.550
CATH Insert Date12 Jun, 2011

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 13 Jun, 2011 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3s2aA01 16 Jun, 2011 3.10.20.90 Assigned
3s2aA02 16 Jun, 2011 2.60.40.150 Assigned
3s2aA03 16 Jun, 2011 1.25.40.70 Assigned
3s2aA04 16 Jun, 2011 3.30.1010.10 Assigned
3s2aA05 16 Jun, 2011 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform