PDB Information

PDB3RJW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.
Vedadi, M., Barsyte-Lovejoy, D., Liu, F., Rival-Gervier, S., Allali-Hassani, A., Labrie, V., Wigle, T.J., Dimaggio, P.A., Wasney, G.A., Siarheyeva, A., Dong, A., Tempel, W., Wang, S.C., Chen, X., Chau, I., Mangano, T.J., Huang, X.P., Simpson, C.D., Pattenden, S.G., Norris, J.L., Kireev, D.B., Tripathy, A., Edwards, A., Roth, B.L., Janzen, W.P., Garcia, B.A., Petronis, A., Ellis, J., Brown, P.J., Frye, S.V., Arrowsmith, C.H., Jin, J.
Nat.Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2011-04-15
Resolution2.560
CATH Insert Date08 May, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 09 May, 2011 Chopped
B 09 May, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3rjwA00 08 Feb, 2013 2.170.270.10 Assigned
3rjwB00 08 Feb, 2013 2.170.270.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q96KQ7 EHMT2_HUMAN Homo sapiens Histone-lysine N-methyltransferase EHMT2
Q96KQ7 EHMT2_HUMAN Homo sapiens Histone-lysine N-methyltransferase EHMT2