PDB Information

PDB3RIL
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-beta-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease
Orwig, S.D., Tan, Y.L., Grimster, N.P., Yu, Z., Powers, E.T., Kelly, J.W., Lieberman, R.L.
Biochemistry
HeaderHydrolase/Hydrolase Inhibitor
Released2011-04-13
Resolution2.4
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3rilA01 08 Jun, 2012 3.20.20.80 Assigned
3rilA02 08 Jun, 2012 2.60.40.1180 Assigned
3rilB01 08 Jun, 2012 3.20.20.80 Assigned
3rilB02 08 Jun, 2012 2.60.40.1180 Assigned
3rilC01 08 Jun, 2012 3.20.20.80 Assigned
3rilC02 08 Jun, 2012 2.60.40.1180 Assigned
3rilD01 08 Jun, 2012 3.20.20.80 Assigned
3rilD02 08 Jun, 2012 2.60.40.1180 Assigned

Uniprot Entries (4)

Accession Gene ID Taxon Description
P04062 GLCM_HUMAN Homo sapiens Acid beta-glucosidase
P04062 GLCM_HUMAN Homo sapiens Acid beta-glucosidase
P04062 GLCM_HUMAN Homo sapiens Acid beta-glucosidase
P04062 GLCM_HUMAN Homo sapiens Acid beta-glucosidase