PDB Information

PDB3RHK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a novel mode of protein kinase inhibition characterized by the mechanism of inhibition of human mesenchymal-epithelial transition factor (c-Met) protein autophosphorylation by ARQ 197.
Eathiraj, S., Palma, R., Volckova, E., Hirschi, M., France, D.S., Ashwell, M.A., Chan, T.C.
J.Biol.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-04-11
Resolution1.940
CATH Insert Date08 May, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 09 May, 2011 Chopped
B 09 May, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3rhkA01 15 May, 2011 3.30.200.20 Assigned
3rhkA02 15 May, 2011 1.10.510.10 Assigned
3rhkB01 15 May, 2011 3.30.200.20 Assigned
3rhkB02 15 May, 2011 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor