PDB 3r2b

PDB Links
Overview

PDB Information

PDB	3R2B
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-based lead identification of ATP-competitive MK2 inhibitors. Barf, T., Kaptein, A., Wilde, S., Heijden, R., Someren, R., Demont, D., Schultz-Fademrecht, C., Versteegh, J., Zeeland, M., Seegers, N., Kazemier, B., Kar, B., Hoek, M., Roos, J., Klop, H., Smeets, R., Hofstra, C., Hornberg, J., Oubrie, A. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2011-03-14
Resolution	2.900
CATH Insert Date	29 May, 2011

PDB Images (37)

3r2b

PDB 3r2b

3r2bA

PDB Chain 3r2bA

3r2bB

PDB Chain 3r2bB

3r2bC

PDB Chain 3r2bC

3r2bD

PDB Chain 3r2bD

3r2bE

PDB Chain 3r2bE

3r2bF

PDB Chain 3r2bF

3r2bG

PDB Chain 3r2bG

3r2bH

PDB Chain 3r2bH

3r2bI

PDB Chain 3r2bI

3r2bJ

PDB Chain 3r2bJ

3r2bK

PDB Chain 3r2bK

3r2bL

PDB Chain 3r2bL

3r2bA01

CATH Domain 3r2bA01

3r2bA02

CATH Domain 3r2bA02

3r2bB01

CATH Domain 3r2bB01

3r2bB02

CATH Domain 3r2bB02

3r2bC01

CATH Domain 3r2bC01

3r2bC02

CATH Domain 3r2bC02

3r2bD01

CATH Domain 3r2bD01

3r2bD02

CATH Domain 3r2bD02

3r2bE01

CATH Domain 3r2bE01

3r2bE02

CATH Domain 3r2bE02

3r2bF01

CATH Domain 3r2bF01

3r2bF02

CATH Domain 3r2bF02

3r2bG01

CATH Domain 3r2bG01

3r2bG02

CATH Domain 3r2bG02

3r2bH01

CATH Domain 3r2bH01

3r2bH02

CATH Domain 3r2bH02

3r2bI01

CATH Domain 3r2bI01

3r2bI02

CATH Domain 3r2bI02

3r2bJ01

CATH Domain 3r2bJ01

3r2bJ02

CATH Domain 3r2bJ02

3r2bK01

CATH Domain 3r2bK01

3r2bK02

CATH Domain 3r2bK02

3r2bL01

CATH Domain 3r2bL01

3r2bL02

CATH Domain 3r2bL02

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	30 May, 2011	Chopped
B	30 May, 2011	Chopped
C	30 May, 2011	Chopped
D	30 May, 2011	Chopped
E	30 May, 2011	Chopped
F	30 May, 2011	Chopped
G	30 May, 2011	Chopped
H	30 May, 2011	Chopped
I	30 May, 2011	Chopped
J	30 May, 2011	Chopped
K	30 May, 2011	Chopped
L	30 May, 2011	Chopped

CATH Domains (24)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3r2bA01	02 Jun, 2011	3.30.200.20	Assigned
3r2bA02	02 Jun, 2011	1.10.510.10	Assigned
3r2bB01	02 Jun, 2011	3.30.200.20	Assigned
3r2bB02	02 Jun, 2011	1.10.510.10	Assigned
3r2bC01	02 Jun, 2011	3.30.200.20	Assigned
3r2bC02	02 Jun, 2011	1.10.510.10	Assigned
3r2bD01	02 Jun, 2011	3.30.200.20	Assigned
3r2bD02	02 Jun, 2011	1.10.510.10	Assigned
3r2bE01	02 Jun, 2011	3.30.200.20	Assigned
3r2bE02	02 Jun, 2011	1.10.510.10	Assigned
3r2bF01	02 Jun, 2011	3.30.200.20	Assigned
3r2bF02	02 Jun, 2011	1.10.510.10	Assigned
3r2bG01	02 Jun, 2011	3.30.200.20	Assigned
3r2bG02	02 Jun, 2011	1.10.510.10	Assigned
3r2bH01	02 Jun, 2011	3.30.200.20	Assigned
3r2bH02	02 Jun, 2011	1.10.510.10	Assigned
3r2bI01	02 Jun, 2011	3.30.200.20	Assigned
3r2bI02	02 Jun, 2011	1.10.510.10	Assigned
3r2bJ01	02 Jun, 2011	3.30.200.20	Assigned
3r2bJ02	02 Jun, 2011	1.10.510.10	Assigned
3r2bK01	02 Jun, 2011	3.30.200.20	Assigned
3r2bK02	02 Jun, 2011	1.10.510.10	Assigned
3r2bL01	02 Jun, 2011	3.30.200.20	Assigned
3r2bL02	02 Jun, 2011	1.10.510.10	Assigned

UniProtKB Entries (12)

Accession	Gene ID	Taxon	Description
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2
P49137	MAPK2_HUMAN	Homo sapiens	MAP kinase-activated protein kinase 2