PDB Information

PDB3R22
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).
Zhang, L., Fan, J., Chong, J.H., Cesena, A., Tam, B.Y., Gilson, C., Boykin, C., Wang, D., Aivazian, D., Marcotte, D., Xiao, G., Le Brazidec, J.Y., Piao, J., Lundgren, K., Hong, K., Vu, K., Nguyen, K., Gan, L.S., Silvian, L., Ling, L., Teng, M., Reff, M., Takeda, N., Timple, N., Wang, Q., Morena, R., Khan, S., Zhao, S., Li, T., Lee, W.C., Taveras, A.G., Chao, J.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-03-11
Resolution2.900
CATH Insert Date14 Aug, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Aug, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3r22A01 16 Aug, 2011 3.30.200.20 Assigned
3r22A02 16 Aug, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A