PDB 3qx3

PDB Information

PDB3QX3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide
Wu, C.C., Li, T.K., Farh, L., Lin, L.Y., Lin, T.S., Yu, Y.J., Yen, T.J., Chiang, C.W., Chan, N.L.
Science
HeaderIsomerase/Dna/Isomerase Inhibitor
Released2011-03-01
Resolution2.160
CATH Insert Date24 Jul, 2011

PDB Images (15)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 01 Aug, 2011 Chopped
B 01 Aug, 2011 Chopped
C 01 Aug, 2011 Rejected
D 01 Aug, 2011 Rejected
E 01 Aug, 2011 Rejected
F 01 Aug, 2011 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3qx3A01 10 Oct, 2013 3.40.50.670 Assigned
3qx3A02 10 Oct, 2013 3.90.199.10 Assigned
3qx3A03 10 Oct, 2013 3.30.1360.40 Assigned
3qx3A04 10 Oct, 2013 1.10.268.10 Assigned
3qx3B01 10 Oct, 2013 3.40.50.670 Assigned
3qx3B02 10 Oct, 2013 3.90.199.10 Assigned
3qx3B03 10 Oct, 2013 3.30.1360.40 Assigned
3qx3B04 10 Oct, 2013 1.10.268.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q02880 TOP2B_HUMAN Homo sapiens DNA topoisomerase 2-beta
Q02880 TOP2B_HUMAN Homo sapiens DNA topoisomerase 2-beta